What is epileptiform syndrome?

Epileptiform syndrome (syndromum epileptiforme) - the general name of paroxysmal disorders (seizures), which are one of the manifestations of the organic process in the brain. It develops in tumors, abscesses, tuberculomas, brain gums, cerebral circulation disorders, parasitic diseases, meningoencephalitis, arachnoiditis, as well as with consequences of perinatal brain damage, early neuroinfections and traumas (residual-organic EC). The emergence of epileptiform syndrome indicates the weighting of the underlying disease. The peculiarities of the clinical manifestations of convulsive seizure often reflect the localization of the lesion focus in the brain.

Of paroxysmal manifestations are more frequent focal (focal) seizures. They can be combined with generalized seizures, which indicates a heavier burden of the underlying disease. Independently generalized with a fall in the Epileptiform syndrome are less common. Sometimes a large seizure develops against the background of constant clonic seizures of individual muscle groups.

Epileptiform syndrome can be manifested only by psychic paroxysms (derealization, depersonalization, dysphoria, twilight states, onyroids), as well as a combination of these paroxysms with focal and generalized paroxysms.

The psychopathological picture of the inter-paroxysmal period is characterized by the presence of a psychoorganic syndrome with various forms of neuropsychic disorders - cerebrostenic, neurotic, psychopathic.

In contrast to epilepsy, typical epileptic personality changes are absent in the Epileptiform syndrome. Persistence and severity of epileptiform syndrome depend on the progress of the underlying disease. It can be transient in the reversibility of the underlying disease, for example, with alcohol intoxication, the consequences of a traumatic brain injury.

Treatment is directed mainly to the underlying disease. As antiepileptic drugs (phenobarbital, benzonale, hexamidine, chloracon, carbamazenin, clonazepam), dehydrogenase (furosemide, diacarb, triampur), detoxifying (unitiol, glutamic acid, sodium thiosulfate) preparations are used as symptomatic agents for paroxysm arrest. Residual organic Epileptiform syndrome is recommended for resorption therapy.