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Buy Gabapentin Online



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  • Names: Gabapentin, Neurontin
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What is Gabapentin?

Gabapentin resembles in its structure gamma-aminobutyric acid (GABA). Now there is evidence that he suppresses the synthesis of glutamate and increases the level of GABA in the brain tissue. The drug is also used to treat neuropathic pain.

Gabapentin is absorbed in the intestine with the help of the system of assimilation of saturated amino acids. This results in a 60% dose absorption in 300 mg, but only 40% of the absorption at a dose of 900 mg. Absorption can be reduced by taking a saturated protein food.

Antacids bind to gabapentin and reduce its bioavailability by 20%, so they can not be taken together. Gabapentin does not bind to plasma proteins and does not cause the production of hepatic enzymes.

It is excreted unchanged in the urine, and therefore its dose should be reduced in case of kidney failure. Frequent side effects are drowsiness, dizziness and ataxia.


Drug information

Read the information below and consult with your doctor before you buy gabapentin online

Indications for use

Partial seizures with secondary generalization and without it in adults and children over 12 years of age (monotherapy); partial seizures with secondary generalization and without it in adults (additional drugs); resistant form of epilepsy in children older than 3 years (additional drugs). Neuropathic pain in patients older than 18 years.

Contraindications

  • Hypersensitivity to any of the components of the drug
  • Age up to 12 years with partial seizures
  • With caution: kidney failure.

Side effects

Do not take medicine if you are allergic to it. If you experience any allergy-related symptoms, such as shortness of breath, hives, swollen tongue, etc., stop using the medication immediately and seek emergency medical attention.

If you find the following symptoms, consult the doctor immediately: stronger cramps; body pain, flu symptoms, swollen glands, high body temperature; light bruising or bleeding, skin rash, tingling, numbness, muscle weakness or pain; pain in the upper stomach, lack of appetite, dark urine color, less urine, skin and yellow eyes; pain in the chest, irregular heartbeat, dyspnea; nausea, vomiting, mental confusion, weight gain; cough and shortness of breath; fast eye movements.

Also report the following side effects: mood changes or behavior; depression or anxiety; agitation; a sense of hostility; anxiety; hyperactivity; suicidal or presumptuous thoughts.

How to take

Inside, regardless of food intake. Epilepsy. Adults and children over the age of 12: the initial dose is 300 mg of gabapentin 3 times a day on the first day, the effective dose is 900-3600 mg / day. The maximum daily dose is 3600 mg (for 3 equal doses). The maximum interval between taking doses when prescribing the drug 3 times a day should not exceed 12 hours.

There may be an appointment according to the following scheme (dose selection step). At a dose of 900 mg: the first day - 300 mg once a day, the second 300 mg twice a day, the third 300 mg 3 times a day; at a dose of 1200 mg: 400 mg once a day, 400 mg twice a day, 400 mg 3 times a day on the first, second and third day, respectively.

Children aged 3-12 years: an effective dose of 25-35 mg / kg / day in 3 equal doses. Titration dose to the effective can be within 3 days: 10 mg / kg / day - the first day, 20 mg / kg / day - the second and 30 mg / kg / day for the third. In a long-term clinical study, tolerability of the drug in doses up to 40-50 mg / kg / day was good.

Possible appointment according to the scheme: with a body weight of 17-25 kg - 600 mg / day, respectively, at 26-36 kg - 900 mg / day, with 37-50 kg - 1200 mg / day, with 51-72 kg - 1800 mg / day . Neuropathy in adults: the initial dose is 300 mg 3 times a day, if necessary, the dose gradually increases to a maximum of 3600 mg / day.

Patients with impaired renal function: with QC greater than 60 ml / min - 400 mg 3 times a day; with QC from 30 to 60 ml / min - 300 mg 2 times a day; with SC from 15 to 30 ml / min - 300 mg once a day; with QC less than 15 ml / min - 300 mg every other day.

Patients who are on hemodialysis who have not previously received gabapentin, it is recommended to administer 300-400 mg in a saturating dose of Gabapentin, and then 200-300 mg every 4 hours of hemodialysis.

Precautions

Neuronthin can interfere with normal vision and reactions. Be careful after taking the medicine while driving or doing other activities that require increased concentration. Do not take antacid preparations 2 hours before or after taking neurontin. It is not known whether neurontin can potentially damage an unborn baby. Tell your doctor if you are pregnant or plan or suspect a pregnancy.

Drug interactions

Perhaps the combined use of gabapentin with other antiepileptic drugs (phenytoin, carbamazepine, valproic acid, phenobarbital), with oral contraceptives (containing norethisterone and / or ethinyl estradiol); Drugs that block tubular secretion (reduce the excretion of gabapentin by the kidneys). Antatsidy (containing Al3 + and Mg2 +) reduce the bioavailability of the drug by about 20% (it is recommended to take 2 hours after taking the antacid). Myelotoxic drugs - increased hematotoxicity of gabapentin (leukopenia).

Missed dose

Take the missed dose of the medication as soon as you remember, but only if there is still more than 4 hours left until the next scheduled dose. If not, skip the missed dose.

Here is the incomplete information, for more details please contact your doctor before buying gabapentin online

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